The couple’s marriage had many ups and downs and inspired parts of the author's books and his wife's only title, Save Me the Waltz.
F Scott Fitzgerald is most famous for having written the Great Gatsby.
Nick Cassavetes, who also was responsible for the 2004 success of The Notebook, will be directing The Beautiful and Damned.
The film gets its title from Fitzgerald's second novel, The Beautiful and Damned and the idea for it was hatched by independent production company the Film Department.
The Beautiful and the Damned is reported to be beginning production in April 2009.
Keira Knightley is currently starring in The Duchess, a period drama set in the 18th Century.
