Marc Lievremont explained: "We are making a turnover, but keeping the balance in the team."
Full-back Anthony Floch will make his debut in the starting line-up for France, and a further two more of the uncapped, hooker Guillem Guirado and scrum-half Julien Tomas, are among the replacement players.
Only six players from the team who started the match against England - Aurelien Rougerie, Francois Trinh-Duc, Dimitri Szarzewski, Nicolas Mas, captain Lionel Nallet and Louis Picamoles, are being kept in the line-up for the game on Sunday.
Vincent Clerc, Damien Traille and Julien Bonnaire are being dropped to the bench, and Cedric Heymans, David Marty, Morgan Parra, Thierry Dusautoir and Lionel Faure are being left out completely.
Jerome Thion, although he has been suffering from an injury, will be the replacement for lock Pascal Pape who is injured, and scrum-half Dimitri Yachvili and flanker Fulgence Ouedraogo are promoted to join the players in starting line-up.
